Stiff-person syndrome

It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises. Symptoms include stiffening in the torso and limbs along with episodes of severe muscle spasms.

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Muscular rigidity often fluctuates ie grows worse and then improves and usually occurs along with the muscle spasms.

. An autoimmune and neurological disorder that causes rigidity and spasms in the trunk and limbs. Spasms can generate enough force to fracture bone. Stiff person syndrome SPS is a very rare disease affecting only one or two people per million.

Like other types of neurological disorders SPS affects your brain and spinal cord central nervous system. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities.

Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility. Medications and immunotherapy maybe prescribed with aqua occupational and physical therapy. People with this condition first experience a stiffening of the muscles of their trunk followed over time by the development of stiffness and rigidity in the legs and other muscles in the body.

Stiff-person syndrome SPS also known as stiff-man syndrome SMS 1 is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness. Stiff person syndrome SPS is a neurological disease with autoimmune features. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS.

Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment. Muscle spasms can be so violent they can dislocate joints and even break bones. Stiff person syndrome SPS is an autoimmune neurological disorder.

Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease. SPS is labeled as a rare disease. Stiff-person syndrome SPS is a rare acquired neurological disorder characterized by progressive muscle stiffness rigidity and repeated episodes of painful muscle spasms.

Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. Stiff person syndrome is a rare autoimmune movement disorder that affects the central nervous system the brain and spinal cord. Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord.

But more people are affected than reported due to misdiagnoses. SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase GAD65.

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